We are seeking a postdoctoral researcher to join a multi-disciplinary team based in the UCLA School of Nursing and Brain Research Institute, led by Dr. Paul Macey, an engineer who is a faculty member in Nursing and who does neuroscience research. The postdoctoral project is centered on advanced neuroimaging of people with obstructive sleep apnea. Working with colleagues from Radiology, Sleep Medicine, Neurobiology, Cardiology, Engineering, and Psychiatry, our group investigates mechanisms, symptoms and treatments for sleep apnea. The current project is to measure the two major neurotransmitters, GABA and glutamate, in many brain areas of people with sleep apnea, and to relate such chemical levels of brain structure and function. The measures involve techniques such as magnetic resonance spectroscopy (MRS) and magnetic resonance imaging, specifically functional MRI (fMRI), diffusion tensor imaging (DTI), arterial spin labeling (ASL), T2 relaxometry, and conventional anatomical MRI. We relate brain changes to psychological symptoms, such as stress, depression and anxiety, and to physical symptoms, such as cardiovascular health and autonomic tone. We do some studies in the home using an mHealth system and we are piloting novel interventions for the sleep condition. Our team takes an integrative view of health, so we are testing standard sleep apnea treatment (CPAP), resistance training, mindfulness (meditation) stress reduction, and we will be starting a diet intervention. The ideal candidate for this position will be interested in working with research participants, including men and women throughout the lifespan. They will be motivated to understand what mechanisms could be contributing to disease, and to help develop novel interventions. They will enjoy learning, and work well with people from varied disciplines. They will be comfortable with technology. They will be motivated to write papers, present their work, and develop and pursue their own research ideas. Particular skills that will be useful are experience with MRI and MRS, either in terms of data collection or analysis; scientific writing; working in clinical settings; familiarity with computers and technology; and software experience including MATLAB, SPSS, R or SAS. However, there will be opportunity to learn required skills. The capacity to learn and the drive to produce results that advance science and the health of patients are far more important than particular skills or experience. If this opportunity excites you, we would love to talk with you!
Interest in health research; some writing experience; comfortable working with men and women across the lifespan; interest in sleep/brain-related disorders and relationship with psychological and cardiovascular symptoms; comfortable with technology; capacity to learn; able to pursue own ideas; comfortable working within a multi-disciplinary team; able to live and work in Los Angeles.
Additional Salary Information: NIH scale; yearly increases. May be flexible for more experienced applicants.
Internal Number: 180801
Paul Macey's research lab at UCLA, based in the School of Nursing and Brain Research Institute.