This is an opportunity for an exceptionally motivated individual to join a dynamic, productive academic laboratory team focused on prevention, treatment, and biology of coronavirus (CoV) infections. The research program encompasses antiviral interventional strategies, CoV replication, and viral evolution. The job scope centers on countermeasures development and experimental study of emerging human CoVs, severe acute respiratory syndrome CoV-2 (SARS-CoV-2) and Middle East respiratory syndrome (MERS)-CoV, the respective causes of COVID-19 and MERS. Primary research activities of this position entail development, evaluation, and mechanistic characterization of candidate CoV therapeutics in the biosafety level (BSL)-2 and BSL-3 laboratories. Secondary responsibilities include involvement in other laboratory research focused on replication, genetic diversity, and molecular biology of human CoVs and the model CoV, murine hepatitis virus. This position anticipates a high degree of independence, advanced technical competence, rigorous protocol adherence, integrated application of diverse technologies, and communication skills commensurate with diverse collaborative interactions internal and external to the laboratory.
The division of pediatric infectious diseases features nationally and internationally-recognized leaders in vaccine development and vaccine safety, bacterial infections such as pertussis and staphylococcus aureus, viral infections such as influenza and coronaviruses (e.g. SARS), pediatric HIV/AIDS, global health, antimicrobial stewardship, and the care of children with compromised immune systems.
Why Choose Infectious Diseases Care at Children's Hospital?
- Our team of ID physicians, nurses, and pharmacists is dedicated to providing the highest-quality care in a compassionate and patient-centered manner.
- Our team is continually at the forefront of new and innovative developments in the diagnosis, treatment, and prevention of pediatric infections.
- Our team works closely with all other specialties within Children's Hospital to provide an individualized, multidisciplinary plan of care for your child.
- Full Time/Non-Exempt Position
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Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient care, VUMC is a community of individuals who come to work each day with the simple aim of changing the world. It is a place where your expertise will be valued, your knowledge expanded and your abilities challenged. It is a place where your diversity -- of culture, thinking, learning and leading -- is sought and celebrated. It is a place where employees know they are part of something that is bigger than themselves, take exceptional pride in their work and never settle for what was good enough yesterday. Vanderbilt's mission is to advance health and wellness through preeminent programs in patient care, education, and research.
VUMC Recent Accomplishments
Because we are committed to providing the best in patient care, education and research, we are proud of our recent accomplishments:
* US News & World Report: #1 Adult Hospital in Tennessee and metropolitan Nashville, named to the Best Hospitals Honor Roll of the top 20 adult hospitals, 10 nationally ranked adult specialty programs, with 3 specialties rated in the top 10 nationally, Monroe Carell Jr. Children's Hospital at Vanderbilt named as one of the Best Children's Hospital in the nation, with 10 out of 10 pediatric specialties nationally ranked.
* Healthcare's Most Wired: Among the nation's 100 "most-wired" hospitals and health systems for its efforts in innovative medical technology.
* Becker's Hospital Review: named as one of the "100 Great Hospitals in America", in the roster of 100 Hospitals and Health Systems with Great Oncology Programs and to its list of the 100 Hospitals with Great Heart Programs.
* The Leapfrog Group: One of only 10 children's hospitals in the to be named at Leapfrog Top Hospital.
* American Association for the Advancement of Science: The School of Medicine has 112 elected fellows
* Magnet Recognition Program: Received our third consecutive Magnet designations.
* National Academy of Medicine: 22 members, elected by their peers in recognition of outstanding achievement
* Human Rights Campaign Healthcare Equality Index: 6th year in a row that Vanderbilt University Medical Center was a Leader in LGBTQ Healthcare Equality.
Key Functions and Responsibilities:
1. Conduct and trouble-shoot research at BSL-2 and BSL-3 with limited supervision
- Plan, design, and implement experiments
- Establish and validate research protocols
- Develop standard operating procedures for data collection, evaluation, and analysis
- Collect and interpret research data
- Generate reports, graphs, charts, tables, etc. of research findings
2. Maintain scientific equipment
3. Exercise discretion and independent judgment to develop methods and procedures for installation, validation, calibration, and operation of scientific equipment
4. Communicate research findings in regular laboratory group conferences and ad hoc with individual lab members to ensure continuing scientific progress required for on-time submission of funding proposals, progress reports, and manuscripts
5. Provide research supervision and training
- Train new lab members for work at BSL-2 and BSL-3
- Provide technical guidance to students, post-doctoral fellows, staff, and faculty as needed
6. Maintain BSL-3 laboratory in continuous readiness for research activities
Monitor supply inventories and order and restock as needed
Monitor and replenish disinfectant solutions
Conduct monthly operational checks and take corrective actions where indicated
Interact with Institutional Biosafety in matters related to required documentation, record-keeping, and ongoing laboratory functionality within prescribed parameters
Lead activities associated with ongoing certification and proper functioning of the laboratory
Coordinate with Institutional Biosafety and Facilities Management as required
- Bachelors Diploma (or equivalent experience) and 4 years relevant experience
A minimum of a bachelor's degree in the biological sciences or other relevant field and prior experience in virology research working at biosafety level 3 is required. Experience with cell and tissue culture; viral replication assays; protein expression, purification, and analysis; and/or antivirals is preferred. The applicant must successfully complete a federal security risk assessment for work in the BSL-3 laboratory.